10 Life Technologies
™
| Genome editing
Recent advances in molecular and cell biology have equipped researchers with powerful genome
(CRISPR) system and transcription activator–like (TAL) effectors, thereby making it relatively
manner. Here is a guide designed to help you select the right technology in the right format for
Genome editing selection guide
Find the right genome editing technology for your application
Do you have
target sequence constraints
(i.e., lack of PAM sequence)?
Will you use
edited cells for
commercial applications?
Multiplex?
GeneArt
nuclease
No
No
No
GeneArt
®
TAL
vector
GeneArt
vector**
Are you working
with plants?
Your
desired
gene edit
Gene
repression
(knockdown)
Custom
effector
domain
Gene
activation
GeneArt
®
TAL VP16 or VP64
activator effector domain
Knockout
or
knock in*
GeneArt
®
TAL KRAB
repressor effector domain
GeneArt
®
TAL
