14 Life Technologies
™
| Genome editing
With their highly flexible but specific targeting, CRISPR-Cas9 systems can
be manipulated and redirected to become powerful tools for genome editing.
CRISPR-Cas9 technology permits targeted gene cleavage and gene editing in a
variety of cells, and because the endonuclease cleavage specificity in CRISPR-
Cas9 systems is guided by RNA sequences, editing can be directed to virtually
any genomic locus by engineering the guide RNA sequence and delivering it along
with the Cas endonuclease to your target cell. Based on your research needs, you
can choose from our two different formats of CRISPR tools: CRISPR-Cas9 all-in-
one expression plasmids, or CRISPR-Cas9 mRNA and gRNA. You can find more
detailed information about both formats on the following pages.
GeneArt
®
CRISPR-Cas9 tools
Rapid and efficient editing with multiplexing capabilities
