Life Technologies

Genome modulation and editing

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5 Life Technologies ™ | Genome editing Design ( Identify targets' sites and design) Deliver (Transfection) Detect and analyze (Screen and enrich) Genome editing • GeneArt ® CRISPR-Cas9 • GeneArt ® TAL effectors Gene modulation • Ambion ® miRNA mimics and inhibitors • Silencer ® Select siRNA Homologus recombination • Flp-In ™ System • Jump-In ™ Ccell engineering platform Lipofectamine ® 3000 reagent Lipofectamine ® RNAiMAX reagent Lipofectamine ® MessengerMAX ™ reagent Lipofectamine ® 2000 reagent Neon ® Transfection System GeneArt ® Genomic Cleavage Detection Kit Real-time PCR assay Ion Torrent ™ next-generation sequencing Cell sorting or bead-based enrichment Complete workflow solution • Complete set of tools and reagents for gene engineering workflow • Custom services available for each step in the workflow or for the entire workflow • Cell line generation services leveraging genome editing tools and cell culture reagents

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