Life Technologies

Genome modulation and editing

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60 Life Technologies ™ | Genome editing Custom cell line engineering services Collaborating as partners to drive discovery Creating stable cell lines is time-consuming and complex. The trusted, experienced developers of GeneArt ® TAL and GeneArt ® CRISPR can offer you custom-designed, stable cell lines generated using one of the most robust and reliable technologies on the market. Deploying quality products throughout the process—everything from Gibco ® cell culture media, reagents, and cell health assays to next-generation sequencing using Ion Torrent ™ sequencers— our scientists will work with you to design your stable cell line and to develop and perform quality-control testing to help ensure that the cell line meets your requirements. All tools and reagents used by our genome engineering service can be purchased and used in your own lab to facilitate your post-service projects. Reagents produced for projects are included in the project as deliverables. What the service includes We draw upon our expertise in creating stable cell lines to design, develop, and validate a custom, stable cell line, as outlined in the diagram below, using validated GeneArt ® TALs or CRISPRs and a cell line that you supply. • Protocol transfer and transfection optimization service • Custom GeneArt ® TALs or GeneArt ® CRISPR production • Validation of custom GeneArt ® TALs or GeneArt ® CRISPR efficacy • Generation of stable cell lines • Quality-control analysis of stable cell line

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